LDAcoop: Analysis of Data from Limiting Dilution Assay (LDA) with or without Cellular Cooperation

Cellular cooperation compromises the established method of calculating clonogenic activity from limiting dilution assay (LDA) data. This tool provides functions that enable robust analysis in presence or absence of cellular cooperation. The implemented method incorporates the same cooperativity module to model the non-linearity associated with cellular cooperation as known from the colony formation assay (Brix et al. (2021) <doi:10.1038/s41596-021-00615-0>: "Analysis of clonogenic growth in vitro." Nature protocols).

Version: 0.1.1
Depends: R (≥ 3.5.0)
Imports: Hmisc
Suggests: knitr, rmarkdown, testthat (≥ 3.0.0)
Published: 2023-10-09
Author: Daniel Samaga [cre, aut], Nikko Brix [aut], Benedek Danko [aut], Kirsten Lauber [aut], Horst Zitzelsberger [aut]
Maintainer: Daniel Samaga <daniel.samaga at helmholtz-munich.de>
BugReports: https://github.com/ZytoHMGU/LDAcoop/issues
License: GPL-3
URL: https://github.com/ZytoHMGU/LDAcoop
NeedsCompilation: no
Materials: README
CRAN checks: LDAcoop results

Documentation:

Reference manual: LDAcoop.pdf
Vignettes: LDAcoop

Downloads:

Package source: LDAcoop_0.1.1.tar.gz
Windows binaries: r-prerel: LDAcoop_0.1.1.zip, r-release: LDAcoop_0.1.1.zip, r-oldrel: LDAcoop_0.1.1.zip
macOS binaries: r-prerel (arm64): LDAcoop_0.1.1.tgz, r-release (arm64): LDAcoop_0.1.1.tgz, r-oldrel (arm64): LDAcoop_0.1.1.tgz, r-prerel (x86_64): LDAcoop_0.1.1.tgz, r-release (x86_64): LDAcoop_0.1.1.tgz

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